Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

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Winning your fantasy football matchups in Week 3 will mean making the right choices on these tough position calls.

With stud wide receiver (and quasi-backup running back) Deebo Samuel Sr. out in Week 3, San Francisco will continue to lean on Mason in a divisional matchup against the Rams. It's a smash opportunity ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...

George Kittle was not in attendance for Thursday's practice session. According to ESPN's Adam Schefter, Kittle is experiencing tightness in ...

San Francisco 49ers left tackle Trent Williams found a possible silver lining in all the injuries the team is dealing with ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

The San Francisco 49ers started off Week 3 on the right foot. After absences and limited participations littered their first ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

With McCaffrey and Samuel out, Rams brace for 49ers' cunning tactics. Kobie Turner stresses the need for execution.