Hustopeče is a town in Břeclav District in the South Moravian Region of the Czech Republic. It has about 6,400 inhabitants. It is known for fru…Hustopeče is a town in Břeclav District in the South Moravian Region of the Czech Republic. It has about 6,400 inhabitants. It is known for fruit and wine growing. The name of the town is derived from the name of the nobleman and alleged founder of Hustopeče, named Úsopek.